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Multiple Sclerosis, Solvents, and PetsA Case-Referent Study
Ulf Flodin, MD;
Birgitta Söderfeldt, MD;
Helle Noorlind-Brage;
Mats Fredriksson;
Olav Axelson, MD
Arch Neurol. 1988;45(6):620-623.
Abstract
• The effect of potential risk factors for multiple sclerosis was evaluated in a case-referent study that encompassed 83 cases and 467 randomized referents. Information on exposure was obtained by questionnaires that were mailed to the subjects. Mantel-Haenszel rate ratios were increased for males for occupational exposure to solvents and welding and for females for leisure time contact with dogs and caged birds. For both sexes, x-ray film examination occurred more frequently among cases than referents, possibly as an effect of early symptoms from the disease itself.
Author Affiliations
From the Departments of Occupational Medicine (Drs Flodin and Axelson, Ms Noorlind-Brage, and Mr Fredriksson) and Neurology (Dr Söderfeldt), University Hospital, Linköping, Sweden.
Footnotes
Accepted for publication Nov 17, 1987.
Reprint requests to Department of Occupational Medicine, University Hospital, S581-85 Linköping, Sweden (Dr Flodin).
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