Subacute structural myopathy associated with human immunodeficiency virus infection

M. F. Gonzales, R. K. Olney, Y. T. So, C. M. Greco, B. A. McQuinn, R. G. Miller and S. J. DeArmond
Department of Pathology, University of California, San Francisco 94143.

An unusual myopathy characterized by selective loss of thick filaments and widespread formation of rod bodies is described in two men, both seropositive for human immunodeficiency virus. We were unable to find any previous reports documenting this combination of morphological abnormalities, which we believe may be related to human immunodeficiency virus infection. Both patients responded to treatment: one, to steroid therapy; the other, to plasmapheresis.

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