You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 45 No. 4, April 1988 TABLE OF CONTENTS
  Archives
  •  Online Features
  OBSERVATIONS
 This Article
 •References
 •Full text PDF
 • Reply to article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit Add to Technorati
What's this?

Severe Orthostatic Hypotension in a Female Carrier of Fabry's Disease

Tatsuro Mutoh, MD; Yasuhiro Senda, MD; Kimiya Sugimura, MD; Yasuo Koike, MD; Yukihiko Matsuoka, MD; Itsuro Sobue, MD; Akira Takahashi, MD; Makoto Naoi, MD

Arch Neurol. 1988;45(4):468-472.


Abstract

• A 21-year-old woman in a family with a history of Fabry's disease showed orthostatic hypotension and whorl-like corneal opacity typical for Fabry's disease. Biochemical studies revealed that she was a heterozygote of the Fabry gene. A variety of autonomic function tests demonstrated both sympathetic and parasympathetic dysfunction. To our knowledge, the present case is the first report of a heterozygous female carrier of Fabry's disease presenting dysfunction of the autonomic nervous system.



Author Affiliations

From the Division of Neurology, Second Department of Internal Medicine, Fukui (Japan) Medical School (Dr Mutoh); the Departments of Neurology (Drs Senda, Sugimura, Koike, Matsuoka, and Takahashi) and Biochemistry (Dr Naoi), Nagoya (Japan) University School of Medicine; and National Chubu Hospital, Nagoya, Japan (Dr Sobue).


Footnotes

Accepted for publication Sept 18, 1987.

Reprint requests to the National Institutes of Health, National Institute of Child Health and Human Development, Section on Growth Factors, Bldg 6, Room 1A07, Bethesda, MD 20892 (Dr Mutoh).



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Neurology and the skin
Hurko and Provost
J. Neurol. Neurosurg. Psychiatry 1999;66:417-430.
FULL TEXT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1988 American Medical Association. All Rights Reserved.