Proximal chronic inflammatory polyneuropathy with multifocal conduction block

W. G. Bradley, R. K. Bennett, P. Good and B. Little
Department of Neurology, University of Vermont College of Medicine, Burlington.

The pathological findings in proximal and distal nerve biopsy specimens are described in a patient with the clinical and electrophysiological features of chronic inflammatory polyneuropathy with multifocal conduction block. Proximal onion bulb hypertrophic changes in the brachial plexus were associated with inflammatory cell infiltrates. In contrast, the sural nerve biopsy specimen showed a mild picture of mixed axonal degeneration and demyelination-remyelination without inflammatory infiltration.