Delayed Hyperemia Following Hypoperfusion in Classic Migraine: Single Photon Emission Computed Tomographic Demonstration

doi:10.1001/archneur.1988.00520260040017

You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.

Vol. 45 No. 2, February 1988

Online Only
	•	Online First Table of Contents

ORIGINAL CONTRIBUTIONS

•	Online Features

This Article
•	References
•	Full text PDF
•	Reply to article
•	Send to a friend
•	Save in My Folder
•	Save to citation manager
•	Permissions

Citing Articles
•	Citation map
•	Citing articles on HighWire
•	Citing articles on Web of Science (121)
•	Contact me when this article is cited

Related Content
•	Similar articles in this journal

Social Bookmarking
	What's this?

Delayed Hyperemia Following Hypoperfusion in Classic Migraine

Single Photon Emission Computed Tomographic Demonstration

Allan Renard Andersen, MD; Lars Friberg, MD; Tom Skyhøj Olsen, MD; Jes Olesen, MD

Arch Neurol. 1988;45(2):154-159.

Abstract

• Regional cerebral blood flow (rCBF) was measured in sevenpatients during classic migraine attacks. Single photon emissioncomputed tomography was performed soon after hospital admission,and three to eight hours, 20 to 24 hours, and one week laterafter the onset of symptoms. Initially reduced rCBF persistingup to three hours was observed in the hemisphere appropriateto the focal neurologic deficit; hyperperfusion was noted laterin the same region in these patients. At 24 hours rCBF was normalin four patients, hyperemia persisted in two patients, and onepatient was not restudied. The area of interest demonstrateda mean decrease of 19% ± 7% in side-to-side asymmetrywhen compared with the contralateral region. In three to eighthours this reversed to a mean increase of 19% ± 4% (delayedhyperemia). No asymmetries were observed after one week. Thelate hyperemic asymmetry often persisted beyond the durationof the clinical headache. It is postulated that this tardiveregional hyperperfusion is a consequence of previous focal arteriolarvasoconstriction. This vascular sequence of events further delineatesthe diagnostic merit of studying rCBF by noninvasive singlephoton emission computed tomography in migraine.

Author Affiliations

From the Departments of Neurology, Rigshospitalet (Dr Andersen) and Gentofte (Drs Olsen and Olesen), University of Copenhagen, and the Department of Clinical Physiology and Nuclear Medicine (Dr Friberg), Bispebjerg Hospital, Copenhagen.

Footnotes

Accepted for publication Sept 18, 1987.

Reprint requests to Department of Neurology, N2081, Rigshospitalet,Blegdamsvej DK 2000 ø, Copenhagen, Denmark (Dr Andersen).

Add to CiteULike CiteULike Add to Connotea Connotea Add to Delicious Delicious Add to Digg Digg Facebook Add to Reddit Reddit Add to Technorati Technorati Twitter What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

CADASIL and migraine: A narrative review
Liem et al.
Cephalalgia 2010;30:1284-1289.
ABSTRACT | FULL TEXT

History of migraine with aura and cortical spreading depression from 1941 and onwards
Tfelt-Hansen
Cephalalgia 2010;30:780-792.
ABSTRACT | FULL TEXT

Changes in Functional Vasomotor Reactivity in Migraine With Aura
Wolf et al.
Cephalalgia 2009;29:1156-1164.
ABSTRACT | FULL TEXT

Posterior Cerebral Hypoperfusion in Migraine Without Aura
Denuelle et al.
Cephalalgia 2008;28:856-862.
ABSTRACT | FULL TEXT

Delayed Hyperperfusion Following Migraine With a Prolonged Aphasic Aura in a Patient With CADASIL
Tfelt-Hansen et al.
Cephalalgia 2008;28:899-902.
FULL TEXT

Migraine Aura Lasting 1-24 h in Children: A Sequence of EEG Slow-Wave Abnormalities Vs. Vascular Events
Parain et al.
Cephalalgia 2007;27:1043-1049.
ABSTRACT | FULL TEXT

Migraine as an inflammatory disorder
Waeber and Moskowitz
Neurology 2005;64:S9-S15.
FULL TEXT

Migraine and other headaches: Associations with Rose angina and coronary heart disease
Rose et al.
Neurology 2004;63:2233-2239.
ABSTRACT | FULL TEXT

Familial Hemiplegic Migraine: Follow-up Findings of Diffusion-Weighted Magnetic Resonance Imaging (MRI), Perfusion-MRI and [99mTc] HMPAO-SPECT in a Patient with Prolonged Hemiplegic Aura
Oberndorfer et al.
Cephalalgia 2004;24:533-539.
ABSTRACT | FULL TEXT

A Case of Hemiplegic Migraine in Childhood: Transient Unilateral Hyperperfusion Revealed by Perfusion MR Imaging and MR Angiography
Masuzaki et al.
Am. J. Neuroradiol. 2001;22:1795-1797.
ABSTRACT | FULL TEXT

Functional Imaging for the Monitoring of Clinical Outcomes of Pharmacotherapy
Bednarczyk
Journal of Pharmacy Practice 2001;14:298-307.
ABSTRACT

Mechanisms of migraine aura revealed by functional MRI in human visual cortex
Hadjikhani et al.
Proc. Natl. Acad. Sci. USA 2001;98:4687-4692.
ABSTRACT | FULL TEXT

Metabolic Characterization of Spinocerebellar Ataxia Type 6
Soong et al.
Arch Neurol 2001;58:300-304.
ABSTRACT | FULL TEXT

Treatment of a prolonged migrainous aura with intravenous furosemide
Rozen
Neurology 2000;55:732-733.
FULL TEXT

Hemiplegic Migraine Induced by Exertion
Razavi et al.
Arch Neurol 2000;57:1363-1365.
ABSTRACT | FULL TEXT

Perfusion Weighted Imaging During Migraine: Spontaneous Visual Aura and Headache
del Rio et al.
Cephalalgia 1999;19:701-707.
ABSTRACT

Investigations Into the Role of Nitric Oxide and the Large Intracranial Arteries in Migraine Headache
Thomsen
Cephalalgia 1997;17:873-895.

Regional Cerebral Blood Flow and Oxygen Metabolism during Migraine with and Without Aura
Andersson et al.
Cephalalgia 1997;17:570-579.
ABSTRACT

Regional cerebral blood flow (rCBF) in migraine during the interictal period: Different rCBF patterns in patients with and without aura
Facco et al.
Cephalalgia 1996;16:161-168.
ABSTRACT

Is Positron Emission Tomography a Useful Tool for Studying Migraine?
Sadzot et al.
Cephalalgia 1995;15:316-322.
ABSTRACT

Cerebral Blood Flow During Migraine Attacks Without Aura and Effect of Sumatriptan
Ferrari et al.
Arch Neurol 1995;52:135-139.
ABSTRACT

Platelet Superoxide Dismutase in Migraine and Tension-Type Headache
Shimomura et al.
Cephalalgia 1994;14:215-218.
ABSTRACT

Chronic Daily Headache--One Disease or Two? Diagnostic Role of Serum Ionized Magnesium
Mauskop et al.
Cephalalgia 1994;14:24-28.
ABSTRACT

Migraine: still a vascular illness?
Olsen
Vasc Med 1991;2:147-159.

Regional Cerebral Blood Flow during Attacks and When Free of Symptoms in a Large Group of Migraine Patients
Friberg et al.
Cephalalgia 1989;9:29-30.

Cerebral Hypoperfusion Followed by Hyperperfusion in Classic Migraine-Reply
Andersen et al.
Arch Neurol 1989;46:606-606.
ABSTRACT

Regional Cerebral Blood Flow in Classic Migraine
Vijayan
Arch Neurol 1989;46:605-605.
ABSTRACT

Cerebral Hypoperfusion Followed by Hyperperfusion in Classic Migraine
Spierings and Graham
Arch Neurol 1989;46:605-606.
ABSTRACT

Mechanisms of migraine aura revealed by functional MRI in human visual cortex
Hadjikhani et al.
Proc. Natl. Acad. Sci. USA 2001;98:4687-4692.
ABSTRACT | FULL TEXT

| | |