Striatal syndrome following hyponatremia and its rapid correction. A manifestation of extrapontine myelinolysis confirmed by magnetic resonance imaging
D. J. Dickoff, M. Raps and M. D. Yahr
Department of Neurology, Mount Sinai School of Medicine, City University of New York, New York.
Several pathologic reports have indicated the occurrence of extrapontine
sites of myelinosis associated with electrolyte disturbance and its rapid
correction. Clinical evidence of the presence of such lesions, however,
have rarely been described. We report a case of a 50-year-old man who
following rapid correction of electrolyte imbalance developed a profound
striatal syndrome. The clinical manifestations, the course of his illness
as well as response to therapy, confirmation of lesion sites by magnetic
resonance imaging (MRI), and abnormalities on visually evoked potentials
are described in detail.
