Cerebral mucormycosis in two cases of acquired immunodeficiency syndrome
L. M. Cuadrado, A. Guerrero, J. A. Garcia Asenjo, F. Martin, E. Palau and D. Garcia Urra
Department of Internal Medicine, Hospital Clinico de San Carlos, Madrid.
We describe two patients with isolated cerebral mucormycosis and acquired
immunodeficiency syndrome (AIDS). Their clinical course was rapid and
fatal; early diagnosis and treatment with amphotericin B did not prevent a
fatal outcome in both cases. Isolated cerebral mucormycosis has not (to our
knowledge) been reported previously in patients with AIDS. Mucormycosis
should be included in the differential diagnosis of central nervous system
infections in intravenous drug abusers with AIDS. A brain biopsy is needed
for the diagnosis of mucormycosis.
