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Luis M. Cuadrado, MD; Antonio Guerrero, MD; Jose A. Lopez Garcia Asenjo, MD; Francisco Martin, MD; Enrique Palau, MD; Daniel Garcia Urra, MD

Arch Neurol. 1988;45(1):109-111.

Abstract
• We describe two patients with isolated cerebral mucormycosis and acquired immunodeficiency syndrome (AIDS). Their clinical course was rapid and fatal; early diagnosis and treatment with amphotericin B did not prevent a fatal outcome in both cases. Isolated cerebral mucormycosis has not (to our knowledge) been reported previously in patients with AIDS. Mucormycosis should be included in the differential diagnosis of central nervous system infections in intravenous drug abusers with AIDS. A brain biopsy is needed for the diagnosis of mucormycosis.

Author Affiliations
From the Departments of Internal Medicine (Drs Cuadrado and Palau), Neurology (Drs Guerrero and Urra), and Pathology (Drs Asenjo and Martin), Hospital Clinico de San Carlos, Madrid.

Footnotes
Accepted for publication May 28, 1987.

Reprints not available.

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