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Gunseli Sarpel, MD; Farooq Chaudry, MD; Walid Hindo, MD

Arch Neurol. 1987;44(7):725-728.

Abstract
• Using a β-permanent magnet (Fonar 3000), we evaluated magnetic resonance imaging of periventricular hyperintensity (PVH) patterns in 60 patients (59 white, 58 men) from the Veterans Administration Hospital, North Chicago, III. Eighty percent of the patients had evidence of PVH, which increased significantly in patients older than age 50 years. In addition to age, history of atherosclerotic cardiovascular disease and extracranial malignancy showed a significant association with PVH. A linear correlation was observed between the severity of PVH and an abnormal neurologic examination. In this retrospective, uncontrolled study, we concluded that PVH incidence among white men is high and increases with age or the presence of cardiovascular disease or extracranial malignancy. The degree of PVH positively correlates with abnormal neurologic evaluation and additional abnormalities seen on magnetic resonance imaging. However, the diseaserelated specificity is as yet undetermined.

Author Affiliations
From the Departments of Neurology (Dr Sarpel), Medicine (Dr Chaudry), and Radiology (Dr Hindo), University of Health Sciences/The Chicago Medical School, and the Neurology (Dr Sarpel), Medicine (Dr Chaudry), and Radiology (Dr Hindo) Services, Veterans Administration Medical Center, North Chicago, Ill.

Footnotes
Accepted for publication March 30, 1987.

Reprint requests to University of Health Sciences/The Chicago Medical School, 3333 Green Bay Rd, Bldg 50, Room 233, North Chicago, IL 60064 (Dr Sarpel).

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