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Clinical Electrophysiologic Studies of HTLV-I-Associated Myelopathy
Kimiyoshi Arimura, MD;
Raymond Rosales, MD;
Mitsuhiro Osame, MD;
Akihiro Igata, MD
Arch Neurol. 1987;44(6):609-612.
Abstract
Six patients with human T-cell lymphotropic virus type I (HTLV-I)—associated myelopathy (HAM) were studied by electrophysiologic methods. Upper-limb short-latency somatosensory evoked potentials showed slight delay of the N9-N20 interpeak latency in one of 12 limbs, while the lower-limb short-latency somatosensory evoked potentials showed prolonged N20-P40 interpeak latency in eight of 12 limbs. Frequent polyphasic potentials and occasional giant spikes were observed in the distal extremities. F-wave conduction velocity was delayed in some patients. Results of the other nerve conduction studies were unremarkable. Our data provide a valuable extension of the clinical examination of HAM and offer encouragement for a more extensive electrophysiologic study of this entity, especially in the spinal cord.
Author Affiliations
From the Third Department of Internal Medicine, Kagoshima (Japan) University Faculty of Medicine.
Footnotes
Accepted for publication Feb 3, 1987.
Reprint requests to Third Department of Internal Medicine, Kagoshima University Faculty of Medicine, 1208-1 Usuki-cho, Kagoshima 890, Japan (Dr Arimura).
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