Thalamic and subcortical gliosis with dementia
J. Moossy, A. J. Martinez, I. Hanin, G. Rao, H. Yonas and F. Boller
We describe two cases of patients with "primary dementia" in whom autopsy
showed marked astrocytosis in several subcortical nuclei, but chiefly in
those of the thalamus. One patient had the onset of symptoms at 31 years of
age and a subacute course. The second patient was an elderly man with a
strong familial history of dementia. These cases offer further evidence
that subcortical lesions, especially in the thalamus, may produce a
dementia that is not always clinically distinguishable from Alzheimer's
disease and other "cortical" dementias.
