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Paul S. Fishman, MD, PhD

Arch Neurol. 1987;44(10):1082-1084.

Abstract
• Autopsy material from patients with posttraumatic paraplegia of long duration was examined to determine the extent of survival of corticospinal axons proximal to the injury. Spinal cord sections from sites above a functionally complete spinal cord injury were examined for the presence of axons, myelin, and gliosis. There was a marked depletion of axons from the corticospinal tract close to the region of injury. There appeared to be a gradual increase in the density of axons within the tract at increasing distance from the injury in all patients. Corticospinal axons appear to retract from the spinal cord injury site, but do not show progressive degeneration even years after a spinal cord injury.

Author Affiliations
From the Department of Neurology, University of Maryland School of Medicine, Baltimore, and the Baltimore Veterans Administration Medical Center.

Footnotes
Accepted for publication July 8, 1987.

Reprint requests to Department of Neurology, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201 (Dr Fishman).

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