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Chronic Human Colchicine Neuropathy and Myopathy
Jack E. Riggs, MD;
Sydney S. Schochet, Jr, MD;
Ludwig Gutmann, MD;
Thomas W. Crosby, MD;
Anthony G. DiBartolomeo, MD
Arch Neurol. 1986;43(5):521-523.
Abstract
• A 43-year-old woman who indiscriminately took colchicine for five years developed a progressive multisystem syndrome that included severe axonal neuropathy and a pathologically striking myopathy. The neuropathy and myopathy were similar to experimental animal colchicine-induced neuromuscular toxicity.
Author Affiliations
From the Departments of Neurology (Drs Riggs, Gutmann, and Crosby), Pathology (Dr Schochet), and Medicine (Dr DiBartolomeo), West Virginia University School of Medicine, Morgantown.
Footnotes
Accepted for publication Aug 1, 1985.
Presented in part at the 37th annual meeting of the American Academy of Neurology, Dallas, May 1, 1985.
Reprint requests to Department of Neurology, West Virginia University Medical Center, Morgantown, WV 26506 (Dr Riggs).
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Arch Neurol 1988;45:245-246.
ABSTRACT
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