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Elissa Koff, PhD; Margaret A. Naeser, PhD; Jean M. Pieniadz; Anne L. Foundas; Harvey L. Levine, MD

Arch Neurol. 1986;43(5):487-491.

Abstract
• Patterns of computed tomographic scan asymmetries in the frontal and occipital regions of the brain were examined in 172 right- and left-handed male and female subjects; these patterns were compared with those published previously to determine which asymmetries were reliable across studies. The patterns observed appeared to be unrelated to handedness or sex and suggested that, especially in the posterior region of the brain, the majority of individuals have left hemispheres longer and wider than their right hemispheres. If anatomic asymmetries are indeed substrates for functional asymmetries, it appears more likely that they are related to at least some aspects of language dominance than to cerebral dominance for handedness.

Author Affiliations
From the Department of Psychology, Wellesley (Mass) College (Dr Koff); the Aphasia Research Center (Drs Koff and Naeser and Mss Pieniadz and Foundas) and Department of Radiology (Dr Levine), Boston Veterans Administration Medical Center; Department of Neurology, Boston University School of Medicine (Dr Naes-er); and Tufts University School of Medicine, Boston (Dr Levine).

Footnotes
Accepted for publication Dec 19, 1985.

Reprint requests to Department of Psychology, Wellesley College, Wellesley, MA 02181 (Dr Koff).

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