This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Neuropsychological Differences

Steven J. Huber, MA; Edwin C. Shuttleworth, MD; George W. Paulson, MD; Maree J. G. Bellchambers, MS; Lawrence E. Clapp

Arch Neurol. 1986;43(4):392-394.

Abstract
• The distinction between cortical and subcortical syndromes of dementia is controversial. Clinical reports suggest that subcortical syndromes (eg, Parkinson's disease) involve less severe intellectual and memory dysfunction and lack the aphasia, agnosia, and apraxia typical of the cortical dementias (eg, dementia of the Alzheimer type). A recent neuropsychological investigation using a standardized procedure failed to confirm the distinction. We examined patients with Alzheimer's disease, patients with Parkinson's disease, and normal controls by using a neuropsychological procedure specifically designed to quantitatively evaluate the proposed clinical differences. The results differentiated these dementia syndromes, and the pattern of performance was consistent with the cortical-subcortical hypothesis.

Author Affiliations
From the Department of Neurology, Ohio State University College of Medicine, Columbus.

Footnotes
Accepted for publication Nov 6, 1985.

Reprint requests to Department of Neurology, 439 Means Hall, 1655 Upham Dr, Columbus, OH 43210 (Mr Huber).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Use of Donepezil for Vascular Dementia: Preliminary Clinical Experience
Mendez et al.
J. Neuropsychiatry Clin. Neurosi. 1999;11:268-270.
ABSTRACT | FULL TEXT  

Magnetic Resonance Imaging Cerebral Abnormalities and Neuropsychologic Test Performance in Elderly Hypertensive Subjects: A Case-Control Study
Schmidt et al.
Arch Neurol 1995;52:905-910.
ABSTRACT  

Meta-analytic Tools for Medical Decision Making: A Practical Guide
Hasselblad and McCrory
Med Decis Making 1995;15:81-96.
ABSTRACT  

Cerebral Blood Flow and Dementia in Parkinson's Disease
Kawabata et al.
J Geriatr Psychiatry Neurol 1991;4:194-203.
ABSTRACT  

Screening for Dementia and Investigating Its Causes
Siu
ANN INTERN MED 1991;115:122-132.
ABSTRACT  

Neuropsychological Differences Between the Dementias of Alzheimer's and Parkinson's Diseases
Huber et al.
Arch Neurol 1989;46:1287-1291.
ABSTRACT  

Cognitive Disturbances in Patients With Relapsing Remitting Multiple Sclerosis
Beatty et al.
Arch Neurol 1989;46:1113-1119.
ABSTRACT  

Dementia: A Review Emphasizing Clinicopathologic Correlation and Brain-Behavior Relationships
Chui
Arch Neurol 1989;46:806-814.
ABSTRACT  

A Comparison of Dementia in Alzheimer's Disease and Multiple Sclerosis
Filley et al.
Arch Neurol 1989;46:157-161.
ABSTRACT  

Cognitive Disturbances in Parkinson's Disease
Beatty et al.
J Geriatr Psychiatry Neurol 1989;2:22-33.
ABSTRACT  

Anterograde and Retrograde Amnesia in Patients With Chronic Progressive Multiple Sclerosis
Beatty et al.
Arch Neurol 1988;45:611-619.
ABSTRACT  

Intellectual Impairment in Parkinson's Disease: Clinical, Pathologic, and Biochemical Correlates
Cummings
J Geriatr Psychiatry Neurol 1988;1:24-36.
ABSTRACT  

Alzheimer's Disease--What the Practicing Clinician Needs to Know
Jenike
J Geriatr Psychiatry Neurol 1988;1:37-46.
 

Magnetic Resonance Imaging Correlates of Dementia in Multiple Sclerosis
Huber et al.
Arch Neurol 1987;44:732-736.
ABSTRACT  

Subcortical Dementia-Reply
Huber et al.
Arch Neurol 1987;44:130-131.
ABSTRACT  

Cortical vs Subcortical Dementia: Neuropsychological Similarities
Rosen
Arch Neurol 1987;44:131-131.
ABSTRACT  

Subcortical Dementia
Mayeux and Stern
Arch Neurol 1987;44:129-130.
ABSTRACT  

Cortical vs Subcortical Dementia: Neuropsychological Similarities-Reply
Huber et al.
Arch Neurol 1987;44:131-131.
ABSTRACT