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Ronald P. Lesser, MD; Michael T. Modic, MD; Meredith A. Weinstein, MD; Paul M. Duchesneau, MD; Hans Lüders, MD; Dudley S. Dinner, MD; Harold H. Morris III, MD; Melinda Estes, MD; Samuel M. Chou, MD; Joseph F. Hahn, MD

Arch Neurol. 1986;43(4):367-371.

Abstract
• Magnetic resonance (MR) (1.5 tesla) studies were performed in ten patients with temporal lobe epilepsy and two with temporofrontal epilepsy. Two patients with temporal lobe epilepsy and one with temporofrontal epilepsy exhibited areas of increased signal intensity on T2-weighted images in the mesiobasal portion of the temporal lobe shown by electroencephalography to be the epileptogenic focus; no analogous abnormalities had been found in these patients on computed tomographic scans. Pathologic studies have not revealed a specific ultrastructural correlate for the MR findings in this group of patients. We found MR to be a useful, noninvasive diagnostic adjunct in the presurgical assessment of some patients with temporal lobe epilepsy. Where abnormalities were found, they corresponded with the epileptogenic focus as defined by electroencephalography.

Author Affiliations
From the Departments of Neurology (Drs Lesser, Lüders, Dinner, and Morris), Radiology (Drs Modic, Weinstein, and Duchesneau), Pathology (Drs Estes and Chou), and Neurosurgery (Dr Hahn), Cleveland Clinic Foundation. Dr Modic is now with Case Western Reserve University School of Medicine, Cleveland.

Footnotes
Accepted for publication Oct 22, 1985.

Reprint requests to the Department of Neurology, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44106 (Dr Lesser).

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