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Petros Tsipouras, MD; Gabor Barabas, MD; Wendy S. Matthews, PhD

Arch Neurol. 1986;43(2):150-152.

Abstract
• The neurologic status of ten patients with osteogenesis imperfecta (OI) was evaluated. Four patients with mild OI (type I) had normal neurologic findings and normal computed tomographic scans. Three of these four patients had macrocephaly. All six patients with severe OI (type III) had cortical atrophy on computed tomographic scan and three were also macrocephalic.

Author Affiliations
From the Departments of Pediatrics (Drs Tsipouras, Barabas, and Matthews) and Biochemistry (Dr Tsipouras), UMDNJ-Rutgers Medical School, Piscataway, NJ. Dr Matthews is now at Monmouth Medical Center, Long Branch, NJ.

Footnotes
Accepted for publication May 20, 1985.

Reprint requests to Department of Biochemistry, UMDNJ-Rutgers Medical School, Piscataway, NJ 08854 (Dr Tsipouras).

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