This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Clinical Correlation in 64 Patients With Multiple Sclerosis

James C. Stevens, MD; Martin R. Farlow, MD; Mary K. Edwards, MD; Pao-lo Yu, PhD

Arch Neurol. 1986;43(11):1145-1148.

Abstract
• Sixty-four patients with possible, probable, or definite multiple sclerosis (McAlpine criteria) were clinically evaluated using the expanded disability status scale (EDSS) and Scripps neurologic rating scale (NRS). All were examined with a 0.15T magnetic resonance scanner using T²- and T¹-weighted images. Correlations between EDSS and NRS scores and severity of disease detected on magnetic resonance imaging were determined. Significant correlations existed between EDSS and NRS with magnetic resonance ratings. Moderate correlations were observed in the motor, cerebellar, and brainstem subgroups of the clinical scales. Significant low correlations existed in the mood/mentation, vision (optic nerves), and bowel/bladder subgroups. Clinical and neuroimaging limitations may account for the lack of higher correlations. Significant correlations suggest the utility of magnetic resonance imaging in monitoring disease progression, and it may prove to be the technique of choice in following up patients with multiple sclero

Author Affiliations
From the Department of Neurology, Indiana University School of Medicine, Indianapolis.

Footnotes
Accepted for publication July 28, 1986.

Reprint requests to Department of Neurology, Indiana University School of Medicine, Emerson Hall, Room 125, 545 Barnhill Dr, Indianapolis, IN 46223 (Dr Farlow).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

MRI measures and their relations with clinical disability in relapsing-remitting and secondary progressive multiple sclerosis
Giugni et al.
Mult Scler 1997;3:221-225.
ABSTRACT  

The Value of Brain Magnetic Resonance Imaging in Multiple Sclerosis
Rudick
Arch Neurol 1992;49:685-686.
ABSTRACT  

Quantitative Multiple Sclerosis Plaque Assessment With Magnetic Resonance Imaging: Its Correlation With Clinical Parameters, Evoked Potentials, and Intra-Blood-Brain Barrier IgG Synthesis
Baumhefner et al.
Arch Neurol 1990;47:19-26.
ABSTRACT  

Cognitive Loss in Multiple Sclerosis: Case Reports and Review of the Literature
Franklin et al.
Arch Neurol 1989;46:162-167.
ABSTRACT