Schilder's (1912) disease. Total cerebral blindness due to acute demyelination

doi:10.1001/archneur.43.1.85

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Vol. 43 No. 1, January 1986

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Schilder's (1912) disease. Total cerebral blindness due to acute demyelination

L. A. Sedwick, T. G. Klingele, R. M. Burde, K. H. Fulling and M. H. Gado

A 51-year-old woman became blind from involvement of both occipital lobes with a confluent lesion demonstrated by computed tomographic scan. Biopsy showed demyelination consistent with Schilder's 1912 variant of diffuse sclerosis. No cytoplasmic inclusions were found on electron microscopy.

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