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A Study of Nine Cases With Unilateral Lesions of the Parietal Lobes

François Lhermitte, MD; Enrique Turell, MD; Dominique LeBrigand; François Chain, MD

Arch Neurol. 1985;42(6):567-573.

Abstract
• Wave P 300 was studied in nine patients with parietal lobe lesions who had visual neglect but no hemianopia. Stimulation of the hemispace contralateral to the lesion showed a lengthening in latency and a decrease in amplitude of P 300, specifically related to visual stimulation. Comparison with results obtained in 14 normal subjects and four patients with localized hemispheric lesions without visual neglect showed that changes in P 300 were specifically related to visual neglect. The parietal lobe lesions may disturb cerebral processes involved in discrimination and visual stimulus evaluation required to perform a task, inducing disturbance of the system responsible for P 300.

Author Affiliations
From the Clinique de Neurologie et de Neuropsychologie, Unité de Recherche de Neuropsychologie (Institute Nationale de la Santé et de la Recherche Médicale U.84), Hôpital de la Salpêtrière, Paris.

Footnotes
Accepted for publication June 13, 1984.

Reprint requests to Clinique de Neurologie et de Neuropsychologie, Hôpital de la Salpêtrière, 47 boulevard de l'Hôpital, 75013 Paris, France (Dr Lhermitte).

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