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Emilio Carranco, MD; John Kareus, DO; Schenley Co, MD; Vincent Peak, PharmD; Saad Al-Rajeh, MD

Arch Neurol. 1985;42(2):187-188.

Abstract
• We describe a 41-year-old woman receiving carbamazepine for epilepsy, in whom concurrent erythromycin stearate administration led to carbamazepine toxicity, including inappropriate antidiuretic hormone syndrome. We review the literature on erythromycin-carbamazepine interaction and discuss the mechanism for such interaction.

Author Affiliations
From the Departments of Internal Medicine (Dr Carranco) and Neurology (Drs Kareus, Co, Peak, and Al-Rajeh), University of Louisville Health Sciences Center.

Footnotes
Accepted for publication July 3, 1984.

Reprint requests to Department of Neurology, University of Louisville, Louisville, KY 40292 (Dr Co).

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