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Jordan Grafman, PhD; Andrés M. Salazar, MD; Herbert Weingartner, PhD; Stephen C. Vance, MD; Christy Ludlow, PhD

Arch Neurol. 1985;42(12):1162-1168.

Abstract
• Persistent memory problems were reported by a 39-year-old man who suffered a penetrating brain wound while serving in Vietnam 15 years earlier. Neuropsychological testing indicated an unusually isolated memory impairment. Computed tomography revealed transection of the columns of the fornix cerebri with no temporal-lobe involvement and minimal thalamic damage. We suggest that the fornix cerebri has a role in the maintenance of information accessibility to both encoding and recall during post-working memory processing and in the organization of verbal information during encoding and/or retrieval for declarative (recall) purposes. These processes are not essential for verbal recognition but can result in decrements on specific laboratory tasks and in social adjustment.

Author Affiliations
From the Department of Clinical Investigation, Vietnam Head-Injury Study, Walter Reed Army Medical Center, Washington, DC (Drs Grafman, Salazar, and Vance), and the National Institutes of Drug Abuse (Dr Weingartner) and Neurological and Communicative Disorders and Stroke (Dr Ludlow), Bethesda, Md.

Footnotes
Accepted for publication April 5, 1985.

The views expressed herein are those of the authors and not of the Department of Defense.

Reprint requests to Department of Clinical Investigation, Vietnam Head-Injury Study, Walter Reed Army Medical Center, Washington, DC 20307-5001 (Dr Grafman).

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