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Bahman Jabbari, MD; Charles G. Maitland, MD; Laura M. Morris, MD; Judith Morales, MD; Carl H. Gunderson, MD

Arch Neurol. 1985;42(11):1072-1074.

Abstract
• Pattern reversal visual evoked potential (VEP) test was performed in 30 asymptomatic patients with neurofibromatosis (NF). All patients had normal visual acuity, visual fields, and ophthalmoscopic examination results. Pattern reversal VEP was abnormal in eight patients (26%). Seven of these patients had computed tomographic scans with reformated orbital views. Orbital computed tomographic scans were abnormal in six patients and in each case showed enlargement of the optic nerve on the side of VEP abnormality. Our data indicate that pattern reversal VEP is a valuable screening test in asymptomatic patients with NF. Because of the high incidence of VEP abnormality in such patients, VEP abnormality must be interpreted cautiously when a patient with NF is suspected of having other diseases or disorders that potentially affect the visual pathways.

Author Affiliations
From the Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, Md, and the Neurology Service, Walter Reed Army Medical Center, Washington, DC.

Footnotes
Accepted for publication Dec 6, 1984.

The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or reflecting the views of the Department of Defense or the Uniformed Services University of the Health Sciences.

Reprint requests to Box 310, Walter Reed Army Medical Center, Washington, DC 20307 (Dr Jabbari).

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