This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (53)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Carl Rosenberg, MD; Kenneth Nudleman, MD; Arnold Starr, MD, PhD

Arch Neurol. 1985;42(10):984-987.

Abstract
• The P3 component of both auditoryevent—and visual-event—related potentials of 13 patients with Huntington's disease was studied and compared with the P3 component of normal patients. The latencies of the patients' P3 components were compared with the latency-age regression lines generated by the normal population in both modalities. A P3 latency was considered abnormal if it fell above the 2-SE limit for the latency-age regression line. The incidence of normal or abnormal P3 latencies in the two modalities was compared with the results of computed tomography, electroencephalography, and neuropsychological testing. Nine patients had abnormal P3 latencies and ten patients had abnormal visual P3 latencies, with seven having abnormal latencies on both tests and 12 having abnormal latencies on one of the two tests. An abnormal P3 latency in one modality did not imply an abnormal P3 latency in the other. An abnormality of the P3 latency did not correlate with an abnormality in results from computed tomography, electroencephalography, or neuropsychological testing.

Author Affiliations
From the Department of Neurology, University of California Medical Center at Irvine, Orange.

Footnotes
Accepted for publication Nov 8, 1984.

Reprint requests to Electrodiagnostics Laboratory, Route 13, University of California at Irvine Medical Center, 101 City Dr S, Orange, CA 92668 (Dr Rosenberg).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Prefrontal Dysfunction and Treatment Response in Geriatric Depression
Kalayam and Alexopoulos
Arch Gen Psychiatry 1999;56:713-718.
ABSTRACT | FULL TEXT  

An Electrophysiological Analysis of Altered Cognitive Functions in Huntington Disease
Munte et al.
Arch Neurol 1997;54:1089-1098.
ABSTRACT  

Event-Related Potentials in Human Immunodeficiency Virus Infection: A Prospective Study
Messenheimer et al.
Arch Neurol 1992;49:396-400.
ABSTRACT  

Event-Related Potential P300 in Multiple Sclerosis: Relation to Magnetic Resonance Imaging and Cognitive Impairment
Honig et al.
Arch Neurol 1992;49:44-50.
ABSTRACT