CNS infection and bacteremia due to clostridium septicum
G. J. Gorse, L. M. Slater, E. Sobol, R. C. Kim, R. M. Wishnow and T. C. Cesario
Central nervous system infection with Clostridium septicum is rare. We
report two fulminant cases of such infection with accompanying bacteremia.
The presence of extensive brain necrosis was striking in our two cases. The
association of C septicum bacteremia with hematologic disease, and with
solid tumors, was present in our cases. We conclude that C septicum should
be considered as a potential cause of life-threatening bacteremia and
meningitis in the compromised host.