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Tourette's Syndrome and Migraine
Gabor Barabas, MD;
Wendy S. Matthews, PhD;
Michael Ferrari, PhD
Arch Neurol. 1984;41(8):871-872.
Abstract
Among 60 patients with Tourette's syndrome (TS), whose mean age was 11.9 years, migraine was prevalent in 26.6%. This figure is substantially greater than that reported for the general population of school-aged children (4.0% to 7.4%) or for two control groups consisting of children with seizure disorders (n = 72) and learning disabilities (n = 62). The prevalence rates for these two control groups were 11.3% and 8.0%, respectively. The hypothesis is offered that the coexistence of TS and migraine in a subgroup of children with TS may reflect a similar abnormality underlying both conditions; specifically, neurohumoral dysfunction involving serotonin metabolism.
Author Affiliations
From the Department of Pediatrics, University of Medicine and Dentistry of New Jersey (UMDNJ)—Rutgers Medical School, Piscataway (Drs Barabas and Matthews); and the Department of Individual and Family Studies, University of Delaware, Newark (Dr Ferrari).
Footnotes
Accepted for publication Oct 13, 1983.
Reprint requests to Division of Pediatric Neurology, Department of Pediatrics, UMDNJ-Rutgers Medical School, PO Box 101, Piscataway, NJ 08854 (Dr Barabas).
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