CSF cholinesterase activity in Gilles de la Tourette's syndrome
H. S. Singer, L. Oshida and J. T. Coyle
Cerebrospinal fluid acetylcholinesterase (AChE) activity was studied as a
possible marker for central cholinergic neuronal function in seven patients
with Gilles de la Tourette's syndrome. No significant differences were
found between CSF AChE activity in untreated or haloperidol-treated
patients and control populations. These data do not appear to support a
pathophysiologic association between the cholinergic system and Gilles de
la Tourette's syndrome.