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David G. Sherman, MD; Linda Goldman, MD; Richard B. Whiting, MD; Karen Jurgensen, MD; Markku Kaste, MD; J. Donald Easton, MD

Arch Neurol. 1984;41(7):708-710.

Abstract
• On retrospective review of records of 150 patients with atrial fibrillation (AF), 31% experienced a stroke or peripheral embolism. The AF was not associated with cardiac valvular disease in 80% of the 150 patients. Most of the cerebral infarcts were large, disabling, and unheralded by transient ischemic attack. The thromboembolism typically occurred in patients whose AF was undetected prior to the infarction. Half of the patients with an ischemic event suffered multiple events, with one fourth of the recurrences arising within two weeks.

Author Affiliations
From the Departments of Medicine, Division of Neurology, University of Texas Health Science Center, San Antonio (Drs Sherman and Easton) and University of Missouri Health Sciences Center, Columbia (Drs Goldman and Whiting), and the Departments of Neurology, University of Texas Health Science Center, Houston (Dr Jurgensen) and University of Helsinki (Dr Kaste).

Footnotes
Accepted for publication Sept 22, 1983.

Reprint requests to Department of Medicine, 7703 Floyd Curl Dr, San Antonio, TX 78284 (Dr Sherman).

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