Thromboembolism in patients with atrial fibrillation
D. G. Sherman, L. Goldman, R. B. Whiting, K. Jurgensen, M. Kaste and J. D. Easton
On retrospective review of records of 150 patients with atrial fibrillation
(AF), 31% experienced a stroke or peripheral embolism. The AF was not
associated with cardiac valvular disease in 80% of the 150 patients. Most
of the cerebral infarcts were large, disabling, and unheralded by transient
ischemic attack. The thromboembolism typically occurred in patients whose
AF was undetected prior to the infarction. Half of the patients with an
ischemic event suffered multiple events, with one fourth of the recurrences
arising within two weeks.
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