Increased intracranial pressure in adrenoleukodystrophy
E. Chaves-Carballo, L. M. Frank and B. A. Chrenka
Increased intracranial pressure developed as a terminal event in a
5-year-old boy with adrenoleukodystrophy. The CSF protein concentration was
420 mg/dL. Computed tomography showed extensive areas of decreased density
in the posterior cerebral white matter. At autopsy, brain weight exceeded
the expected value by 20%, and white matter water content was 87.6%
(expected value, 72.5%). In rare instances, brain edema may contribute to
the development of increased intracranial pressure in adrenoleukodystrophy.
