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Enrique Chaves-Carballo, MD; L. Matthew Frank, MD; Blair A. Chrenka, MD

Arch Neurol. 1984;41(3):339-340.

Abstract
• Increased intracranial pressure developed as a terminal event in a 5-year-old boy with adrenoleukodystrophy. The CSF protein concentration was 420 mg/dl. Computed tomography showed extensive areas of decreased density in the posterior cerebral white matter. At autopsy, brain weight exceeded the expected value by 20%, and white matter water content was 87.6% (expected value, 72.5%). In rare instances, brain edema may contribute to the development of increased intracranial pressure in adrenoleukodystrophy.

Author Affiliations
From the Departments of Neurology (Drs Chaves-Carballo and Frank), Pediatrics (Drs Chaves-Carballo, Frank, and Chrenka), and Pathology (Dr Chrenka), Eastern Virginia Medical School, and Children's Hospital of the King's Daughters, Norfolk, Va.

Footnotes
Accepted for publication June 29, 1983.

Reprint requests to Department of Neurology, Eastern Virginia Medical School, 855 W Brambleton Ave, Norfolk, VA 23510 (Dr Chave-Carballo).

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ABSTRACT