Essential myoclonus in a kindred with familial malignant melanoma
J. G. Nutt and T. D. Bird
We studied a kindred in which three members had essential myoclonus and
seven members had malignant melanoma. Two of the persons with myoclonus had
melanoma and the third carried the genetic predisposition for melanoma. The
coexistence of the two disorders in these patients could represent
coincidence, linkage between the two dominant genes, or the pleiotropic
expression of a single gene affecting neuroectodermal derivatives.