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Essential Myoclonus in a Kindred With Familial Malignant Melanoma
John G. Nutt, MD;
Thomas D. Bird, MD
Arch Neurol. 1984;41(2):189-191.
Abstract
• We studied a kindred in which three members had essential myoclonus and seven members had malignant melanoma. Two of the persons with myoclonus had melanoma and the third carried the genetic predisposition for melanoma. The coex-istence of the two disorders in these patients could represent coincidence, linkage between the two dominant genes, or the pleiotropic expression of a single gene affecting neuroectodermal derivatives.
Author Affiliations
From the Department of Neurology, Oregon Health Sciences University, Portland (Dr Nutt), and the Department of Medicine, University of Washington School of Medicine, Seattle, and the Seattle Veterans Administration Hospital (Dr Bird).
Footnotes
Accepted for publication April 14, 1983.
Reprint requests to Department of Neurology, Oregon Health Sciences University, Portland, OR 97201 (Dr Nutt).
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