Changes in the incidence of amyotrophic lateral sclerosis in Israel
E. Kahana and N. Zilber
The incidence of amyotrophic lateral sclerosis (ALS) in Israel was
determined for the period 1959 through 1974. A total of 246 patients with
ALS was ascertained. The male-female ratio was 1.62:1. The average annual
age-adjusted incidence per 100,000 persons increased during this period by
41%. The increase was almost entirely due to a higher rate in persons more
than 60 years of age and was greater in women than in men. This led to a
decrease in the male-female ratio. The mean age of onset increased from
52.8 to 58.6 years during the same period. The increment in incidence could
not be explained by better case ascertainment or increased life expectancy,
but greater precision in diagnosis of ALS in the aged may have partially
contributed to the increase.
Descriptive epidemiology of amyotrophic lateral sclerosis: new evidence and unsolved issues
Logroscino et al.
J. Neurol. Neurosurg. Psychiatry 2008;79:6-11.
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Epidemiology and clinical features of amyotrophic lateral sclerosis in Ireland between 1995 and 2004
O'Toole et al.
J. Neurol. Neurosurg. Psychiatry 2008;79:30-32.
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Ethnic variation in the incidence of ALS: A systematic review
Cronin et al.
Neurology 2007;68:1002-1007.
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Incidence of amyotrophic lateral sclerosis in southern Italy: a population based study
Logroscino et al.
J. Neurol. Neurosurg. Psychiatry 2005;76:1094-1098.
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Excess incidence of ALS in young Gulf War veterans
Haley
Neurology 2003;61:750-756.
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The epidemiology of ALS in Modena, Italy
Mandrioli et al.
Neurology 2003;60:683-689.
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Incidence of ALS in Italy: Evidence for a uniform frequency in Western countries
Neurology 2001;56:239-244.
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Incidence and prevalence of ALS in Ireland, 1995-1997: A population-based study
Traynor et al.
Neurology 1999;52:504-504.
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