You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 41 No. 10, October 1984 TABLE OF CONTENTS
  Archives
  •  Online Features
  ARTICLE
 This Article
 • Reply to article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal

Pneumococcal meningitis. Late neurologic sequelae and features of prognostic impact

V. Bohr, O. B. Paulson and N. Rasmussen

We interviewed and neurologically reexamined 94 patients who had previous pneumococcal meningitis. The findings were allocated into groups with and without a causal relationship to the meningitis. The main sequelae after meningitis were dizziness (23%), tiredness (22%), mild memory deficits (21%), and gait ataxia (18%), whereas other focal neurologic signs were rare. By a rating (0 to 5) of the presence and severity of sequelae after meningitis, 54% of the patients were found to have sequelae. The clinical condition at the time of acute illness was studied in subgroups of patients who had different neurologic sequelae or high sequelae ratings. Gait ataxia was associated with a state of agitation and confusion when the patient was admitted for meningitis. High sequelae ratings on reexamination were associated with an affected consciousness at the acute stage of the disease and with high numbers of WBCs in the CSF at the time of hospitalization.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Ly-6G+CCR2- Myeloid Cells Rather Than Ly-6ChighCCR2+ Monocytes Are Required for the Control of Bacterial Infection in the Central Nervous System
Mildner et al.
J. Immunol. 2008;181:2713-2722.
ABSTRACT | FULL TEXT  

Pneumococcal Cell Wall-Induced Meningitis Impairs Adult Hippocampal Neurogenesis
Hoffmann et al.
Infect. Immun. 2007;75:4289-4297.
ABSTRACT | FULL TEXT  

Interplay of Pneumococcal Hydrogen Peroxide and Host-Derived Nitric Oxide
Hoffmann et al.
Infect. Immun. 2006;74:5058-5066.
ABSTRACT | FULL TEXT  

Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice
Djukic et al.
Brain 2006;129:2394-2403.
ABSTRACT | FULL TEXT  

Neuropsychological sequelae of bacterial and viral meningitis
Schmidt et al.
Brain 2006;129:333-345.
ABSTRACT | FULL TEXT  

CD14 deficiency leads to increased MIP-2 production, CXCR2 expression, neutrophil transmigration, and early death in pneumococcal infection
Echchannaoui et al.
J. Leukoc. Biol. 2005;78:705-715.
ABSTRACT | FULL TEXT  

Aquaporin-4 Gene Disruption in Mice Reduces Brain Swelling and Mortality in Pneumococcal Meningitis
Papadopoulos and Verkman
J. Biol. Chem. 2005;280:13906-13912.
ABSTRACT | FULL TEXT  

Streptococcus pneumoniae-Induced Inhibition of Rat Ependymal Cilia Is Attenuated by Antipneumolysin Antibody
Hirst et al.
Infect. Immun. 2004;72:6694-6698.
ABSTRACT | FULL TEXT  

Bacterial Inhibition of Phosphatidylcholine Synthesis Triggers Apoptosis in the Brain
Zweigner et al.
JEM 2004;200:99-106.
ABSTRACT | FULL TEXT  

Experimental Pneumococcal Meningitis: Impaired Clearance of Bacteria from the Blood Due to Increased Apoptosis in the Spleen in Bcl-2-Deficient Mice
Wellmer et al.
Infect. Immun. 2004;72:3113-3119.
ABSTRACT | FULL TEXT  

Reprogramming the Host Response in Bacterial Meningitis: How Best To Improve Outcome?
van der Flier et al.
Clin. Microbiol. Rev. 2003;16:415-429.
ABSTRACT | FULL TEXT  

Pneumococcal meningitis in adults: Spectrum of complications and prognostic factors in a series of 87 cases
Kastenbauer and Pfister
Brain 2003;126:1015-1025.
ABSTRACT | FULL TEXT  

Decreased Virulence of a Pneumolysin-Deficient Strain of Streptococcus pneumoniae in Murine Meningitis
Wellmer et al.
Infect. Immun. 2002;70:6504-6508.
ABSTRACT | FULL TEXT  

Oxidative stress in bacterial meningitis in humans
Kastenbauer et al.
Neurology 2002;58:186-191.
ABSTRACT | FULL TEXT  

Relative Roles of Pneumolysin and Hydrogen Peroxide from Streptococcus pneumoniae in Inhibition of Ependymal Ciliary Beat Frequency
Hirst et al.
Infect. Immun. 2000;68:1557-1562.
ABSTRACT | FULL TEXT  

Does This Adult Patient Have Acute Meningitis?
Attia et al.
JAMA 1999;282:175-181.
ABSTRACT | FULL TEXT  

The Origin and Function of Soluble CD14 in Experimental Bacterial Meningitis
Cauwels et al.
J. Immunol. 1999;162:4762-4772.
ABSTRACT | FULL TEXT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1984 American Medical Association. All Rights Reserved.