This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (7)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Leo Paljärvi, MD; Kristian Karjalainen, MD; Hannu Kalimo, MD

Arch Neurol. 1984;41(1):39-42.

Abstract
• Five lectins were used as fluorescence microscopic markers for sugar residues in skeletal muscle. Biopsy specimens were taken from patients with X-linked muscular dystrophy (Duchenne's and Becker's), patients with other neuromuscular diseases, and normal controls. In both the controls and the pathologic samples, concanavalin A gave a bright fluorescence of the myofiber surface, whereas soybean agglutinin and Dolichos biflorus agglutinin fluorescence was negative. Peanut agglutinin and wheat germ agglutinin were more avidly bound to the sarcolemma and/or endomysial connective tissue in the patients with X-linked muscular dystrophy than in the controls or the patients with other conditions. The altered saccharide pattern may reflect either a myofiber membrane change or a specific mesenchymal reaction in the dystrophic muscle.

Author Affiliations
From the Department of Pathology, and Neurology University of Turku (Finland).

Footnotes
Accepted for publication March 3, 1983.

Read before the 24th Scandinavian Congress of Neurology, Copenhagen, June 11, 1982.

Reprint requests to the Department of Pathology, University of Turku, SF-20520 Turku 52, Finland (Dr Paljärvi).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Reduction of UDP-N-acetylglucosamine 2-Epimerase/N-Acetylmannosamine Kinase Activity and Sialylation in Distal Myopathy with Rimmed Vacuoles
Noguchi et al.
J. Biol. Chem. 2004;279:11402-11407.
ABSTRACT | FULL TEXT