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  Vol. 40 No. 7, July 1983 TABLE OF CONTENTS
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Myeloneuropathy and Macrocytosis Associated With Nitrous Oxide Abuse

Guillermo Blanco, MD; Henry A. Peters, MD

Arch Neurol. 1983;40(7):416-418.


Abstract

• After four months of excessive nitrous oxide (N2O) exposure, a dentist had myeloneuropathy with spastic paraparesis, Lhermitte's sign, sensory shading, loss of position and vibration sense, ataxia, and impotence. Macrocytosis, hypersegmented neutrophils, and a reduced vitamin B12 level were associated with normal findings on gastric analysis and Schilling test. Complete hematologic and neurologic recovery followed N2O avoidance and vitamin therapy for six months.



Author Affiliations

From the Department of Neurology, University of Wisconsin Medical School, Madison.


Footnotes

Accepted for publication Nov 13, 1982.

Reprint requests to Department of Neurology, University of Wisconsin Medical School, 600 Highland Ave, Madison, WI 53792 (Dr Peters).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Protracted Lhermitte's Sign Following Head and Neck Irradiation
Thornton et al.
Arch Otolaryngol Head Neck Surg 1991;117:1300-1303.
ABSTRACT  

Is Nitrous Oxide a Dangerous Anesthetic for Vitamin B12-Deficient Subjects?
Schilling
JAMA 1986;255:1605-1606.
ABSTRACT  





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