This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (21)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Effects of Hyperthermia on Test Results

Kenneth R. Phillips, MS; Alfred R. Potvin, PE, PhD; Karl Syndulko, PhD; Stanley N. Cohen, MD; Wallace W. Tourtellotte, MD, PhD; Janet H. Potvin, PhD

Arch Neurol. 1983;40(3):159-164.

Abstract
• Data on critical frequency of photic driving (CFPD), frequency following response (FFR), and visual, somatosensory (peroneal nerve), and brain-stem auditory evoked potentials (EPs) were obtained from 20 patients who had clinically definite multiple sclerosis and ten healthy normal subjects in a controlled, balanced study under normothermic and hyperthermic (+1 °C) conditions with a test-retest interval of one week. Normal subjects' test results showed no changes during hyperthermia. Patients' EP and CFPD data correlated well with history, clinical signs, and symptoms during both normothermia and hyperthermia. The FFR test data were equivocal and not fully analyzed. Data from the four other tests showed additional patient abnormalities during hyperthermia. Multimodality testing increased the number of patient abnormalities compared with single tests, and the number increased further during hyperthermia. Test-retest reproducibility was higher during hyperthermia.

Author Affiliations
From the Biomedical Engineering Program (Mr Phillips and Dr A. R. Potvin) and the Department of English (Dr J. H. Potvin), The University of Texas at Arlington; the Neurology and Research Service, Veterans Administration Wadsworth Medical Center, Los Angeles (Drs Syndulko, Cohen, and Tourtellotte); and the Department of Neurology, School of Medicine, UCLA (Drs Cohen and Tourtellotte).

Footnotes
Accepted for publication June 30, 1982.

Reprint requests to Biomedical Engineering Program, PO Box 19138, The University of Texas at Arlington, Arlington, TX 76019 (Dr A. R. Potvin).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Measuring evoked responses in multiple sclerosis
Comi et al.
Mult Scler 1999;5:263-267.
ABSTRACT  

Effects of Temperature in Multiple Sclerosis: A Review of the Literature
Syndulko et al.
Neurorehabil Neural Repair 1996;10:23-34.
ABSTRACT