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Clinical Characteristics of Ten Cases

Toshikatsu Indo, MD; Kazuya Ando, MD

Arch Neurol. 1982;39(8):494-496.

Abstract
• Clinical characteristics of ten patients with metoclopramide hydrochloride—induced parkinsonism were studied. This condition was found to be more common in aged women and developed subacutely with bilateral symptoms. Clinically, metoclopramide-induced parkinsonism is sometimes accompanied by a rest tremor and may therefore be confused with Parkinson's disease. It is distinct from the latter in that orolingual dyskinesia and postural tremor are often found before the administration of antiparkinsonian drugs. The patients with metoclopramide-induced parkinsonism made a complete recovery within a few months after administration of the drug was discontinued.

Author Affiliations
From the Department of Neurology, Gifu (Japan) Prefectural Tajimi Hospital (Dr Indo), and the National Center for Nervous, Mental and Muscular Disorders, Tokyo (Dr Ando).

Footnotes
Accepted for publication Dec 2, 1981.

Read in part before the annual meeting of the Research Committee on Degenerative CNS Diseases, Ministry of Health and Welfare of Japan, Tokyo, Jan 1, 1980.

Reprint requests to Department of Neurology, Gifu Prefectural Tajimi Hospital, 5-161 Maehata-cho, Tajimi-shi, Gifu, Japan (Dr Indo).

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