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Implications of Therapeutic Response to Levodopa and Carbamazepine

Bhuwan P. Garg, MB, BS

Arch Neurol. 1982;39(6):376-377.

Abstract
• Sporadic, autosomal recessive and dominant forms of dystonia musculorum deformans have been recognized. This communication reports the results of treatment of six patients with this condition. Two patients with the recessive form responded to levodopa therapy. Three patients who responded to carbamazepine therapy probably have the dominant form. In one patient, response to carbamazepine therapy was equivocal. It is suggested that such therapeutic responsiveness may reflect underlying biochemical differences in the recessive and dominant forms of the disease.

Author Affiliations
From the Department of Neurology (Child), Indiana University School of Medicine, Indianapolis.

Footnotes
Accepted for publication Oct 4, 1981.

Reprint requests to Department of Neurology, Riley Hospital N-102, 1100 W Michigan St, Indianapolis, IN 46223 (Dr Garg).