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II. Thalamic Lesions in a Case of Developmental Dyslexia

Albert M. Galaburda, MD; David Eidelberg, MD

Arch Neurol. 1982;39(6):333-336.

Abstract
• The cytoarchitecture of the brain of a patient with developmental dyslexia was analyzed. The cortical abnormalities, consisting of micropolygyria encompassing most of posterior temporoparietal area and ectopic cell collections elsewhere have been described previously. In this study, the posterior thalamus was likewise analyzed, and a bilateral disruption of cytoarchitecture was noted in the medial geniculate nucleus and the lateralis posterior nucleus, a nuclear group of probable relevance to language found to be asymmetric.

Author Affiliations
From the Neurological Units of the Beth Israel Hospital (Drs Galaburda and Eidelberg) and Boston City Hospital (Dr Galaburda); Departments of Neurology, Harvard Medical School (Drs Galaburda and Eidelberg) and Boston University School of Medicine (Dr Galaburda); and the Dana Research Institute of the Beth Israel Hospital (Drs Galaburda and Eidelberg), Boston.

Footnotes
Accepted for publication Sept 10, 1981.

Reprint requests to Neurological Unit, Beth Israel Hospital, 330 Brookline Ave, Boston, MA 02215 (Dr Galaburda).

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