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Mark J. Kupersmith, MD; Eric Shakin; Irwin M. Siegel, PhD; Abraham Lieberman, MD

Arch Neurol. 1982;39(5):284-286.

Abstract
• Visual evoked potentials (VEPs) and contrast sensitivity measurements were determined in normally sighted patients with Parkinson's disease (PD). Prolonged latencies of the first major positive (P₁₀₀) wave of the VEP elicited by an alternating vertical grating were noted. The delay in latency was positively correlated with the severity of the movement disability. Subjective testing of contrast thresholds demonstrated significant elevation of thresholds in PD. Electroretinographic oscillatory potentials were elicited to determine if the delay in P₁₀₀ latency was of retinal origin. No specific lesion could be identified to account for the abnormality in VEP or in contrast testing results.

Author Affiliations
From the Departments of Neurology (Drs Kupersmith and Lieberman) and Ophthalmology (Drs Kupersmith, Shakin, and Siegel), New York University Medical Center.

Footnotes
Accepted for publication July 1, 1981.

Reprint requests to Department of Ophthalmology, New York University Medical Center, 550 First Ave, New York, NY 10016 (Dr Kupersmith).

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