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Wolfgang R. Kiessling, MD

Arch Neurol. 1982;39(4):241-242.

Abstract
• In an endemic goiter area of West Germany (incidence of goiter, 19% to 32%), thyroid function was evaluated in 44 patients with amyotrophic lateral sclerosis (ALS) with radioimmunoassay of triiodothyronine, thyroxine, thyroxine-binding globulin, and thyroid-stimulating hormone, including the protirelin stimulation test. The presence of circulating anti-thyroid antibodies was sought by hemagglutination techniques. All patients were found to be euthyroid and thyroid antibody—negative. Clinical examination disclosed concomitant goiter in 36% (16/ 44). The data suggest that thyroid status is not relevant to the pathogenesis of ALS.

Author Affiliations
From the Neurologische Universitätsklinik, Würzburg, West Germany.

Footnotes
Accepted for publication May 11, 1981.

Reprint requests to Neurologische Universitätsklinik, Josef-Schneider-Str 11, D-8700 Würzburg, West Germany (Dr Kiessling).

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