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A Case Report

Brian A. Anderson, MD; P. Vincent Young, MD; Walter F. Kean, MB, ChB, FRCP(C); Samuel K. Ludwin, MD; Peter R. Galbraith, MD; Tassos P. Anastassiades, MD

Arch Neurol. 1982;39(3):188-190.

Abstract
• A child, three years after bone marrow transplantation for aplastic anemia, had polymyositis develop as part of chronic graft vs host disease (GVHD). Previous reports have alluded to nonspecific musculoskeletal complaints during life and the occasional finding of necrotizing myositis at autopsy. This report describes the recognition during life, biopsy findings, and response to treatment of inflammatory myopathy during the course of GVHD.

Author Affiliations
From the Departments of Pathology (Drs Anderson and Ludwin) and Medicine (Drs Young, Kean, Galbraith, and Anastassiades), Queen's University and Kingston (Ontario) General Hospital.

Footnotes
Accepted for publication May 23, 1981.

Reprint requests to Department of Pathology, Queen's University, Kingston K7L 3N6, Ontario, Canada (Dr Ludwin).

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