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Inclusion Body Myositis Associated With Sjögren's Syndrome
David Chad, MD, FRCP(C);
Paul Good;
Lester Adelman, MD;
Walter G. Bradley, DM, FRCP;
John Mills, MD
Arch Neurol. 1982;39(3):186-188.
Abstract
• A patient with polymyositis had the pathological hallmarks of inclusion body myositis (IBM) as well as features that to our knowledge have never before been reported in IBM—an associated collagenvascular disease (Sjögren's syndrome) and tubuloreticular structures in capillary endothelial cells. The pathogenesis of IBM is unknown, but its coexistence with Sjögren's syndrome suggests that immune mechanisms may play a role in producing muscle damage.
Author Affiliations
From the Departments of Neurology (Drs Chad, Adelman, and Bradley and Mr Good) and Pathology (Dr Adelman), Tufts New England Medical Center, and the Department of Medicine, Harvard Medical School, Massachusetts General Hospital (Dr Mills), Boston.
Footnotes
Accepted for publication May 23, 1981.
Reprint requests to Department of Neurology, New England Medical Center Hospital, 171 Harrison Ave, Boston, MA 02111 (Dr Chad).
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