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Scott Haldeman, MD, PhD; Michael Glick, MD; Narender N. Bhatia, MD; William E. Bradley, MD; Bonnie Johnson, RN

Arch Neurol. 1982;39(11):698-701.

Abstract
• The conditions of three patients with advanced-stage multiple sclerosis and symptoms related to bowel and bladder function were evaluated using colonometry, cystometry, and somatosensory evoked responses from the posterior tibial nerve. The colonometrograms and cystometrograms showed notable hyperreflexia and reduced filling capacity when compared with neurologically intact patients. The neurological lesions were localized to above the conus medullaris by recording normal somatosensory responses at L-1 and abnormal responses over the scalp. This combination of tests are important in the documentation of bowel and bladder dysfunction, the localization of the neurological lesion causing the symptoms, and the determination of treatment of bowel and bladder symptoms in patients with multiple sclerosis.

Author Affiliations
From the Neurology Service (Drs Haldeman and Bradley, and Ms Johnson), Veterans Administration Medical Center, Long Beach, Calif, and the Departments of Neurology (Drs Haldeman and Bradley), Gynecology and Obstetrics (Dr Bhatia), and Gastroenterology (Dr Glick), University of California, Irvine.

Footnotes
Accepted for publication Dec 1, 1981.

Reprint requests to Neurology Service, Veterans Administration Medical Center, 5901 E Seventh St, Long Beach, CA 90822 (Dr Haldeman).

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