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Effects of Anticholinergic Drugs on Memory in Parkinson's Disease
Menachem Sadeh, MD;
Jackson Braham, FRCP;
Michaela Modan, MSc
Arch Neurol. 1982;39(10):666-667.
Abstract
Forty-one parkinsonian patients were examined for the effect of anticholinergic drugs on memory function. Nineteen were tested while both receiving and not receiving treatment, 11 while receiving treatment only, and 11 others while not receiving such medication. Significant deterioration of performance on a test for intermediate memory was observed in those receiving therapy. The group of patients as a whole compared unfavorably with healthy, untreated control subjects, particularly for intermediate memory.
Author Affiliations
From the Departments of Neurology (Drs Sadeh and Braham) and Clinical Epidemiology (Ms Modan), Chaim Sheba Medical Center, Tel Hashomer, Israel, and the Sackler School of Medicine (Drs Sadeh and Braham), Tel Aviv (Israel) University.
Footnotes
Accepted for publication Dec 2, 1981.
Reprint requests to Department of Neurology, Sheba Medical Center, Tel Hashomer, Israel (Dr Braham).
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