 |
|
Clinical and Electrophysiological Studies in Primary Lateral Sclerosis
Louis S. Russo, Jr, MD
Arch Neurol. 1982;39(10):662-664.
Abstract
• Primary lateral sclerosis denotes a clinical state with the insidious onset and slow progression of neurological dysfunction limited to the corticospinal tract. We describe four unrelated patients with spastic paraparesis and normal sensory and cerebellar function. None had a family history of neurological disease. All had been symptomatic for more than five years and had been followed up for 25 to 42 months without manifesting signs of involvement of other systems. Laboratory and roentgenographic evaluations demonstrated no contributory abnormality. Motor and sensory nerve conduction studies and electromyography disclosed no abnormality. These negative findings support the position that primary lateral sclerosis is a distinct neurological entity.
Author Affiliations
From the Neurology Service, University Hospital of Jacksonville (Fla), and the Department of Neurology, University of Florida College of Medicine, Gainesville.
Footnotes
Accepted for publication Jan 20, 1982.
Reprint requests to 655 W Eighth St, Jacksonville, FL 32209 (Dr Russo).
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
The first ALS2 missense mutation associated with JPLS reveals new aspects of alsin biological function
Panzeri et al.
Brain 2006;129:1710-1719.
ABSTRACT
| FULL TEXT
Primary lateral sclerosis: clinical, neurophysiological, and magnetic resonance findings
Kuipers-Upmeijer et al.
J. Neurol. Neurosurg. Psychiatry 2001;71:615-620.
ABSTRACT
| FULL TEXT
Does primary lateral sclerosis exist?: A study of 20 patients and a review of the literature
Le Forestier et al.
Brain 2001;124:1989-1999.
ABSTRACT
| FULL TEXT
Identifying Persistent Adverse Effects of Anticholinergic Drugs in the Elderly
Katz et al.
J Geriatr Psychiatry Neurol 1988;1:212-217.
ABSTRACT
|
