This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal

David S. Bachman, MD

Arch Neurol. 1982;39(1):49-52.

Abstract
• Nineteen babies with infantile spasms were treated with valproic acid over a two-year period. Eleven of the patients were also treated with purified corticotropin, but in no cases were the two drugs used simultaneously. Approximately 40% of the patients had good control of their infantile spasms with valproic acid. Side effects from valproic acid in these babies were not frequent and were, for the most part, minor. Though the percentage of infants with infantile spasms responding to valproic acid may be less than the percentage responding to corticotropin, the incidence and severity of side effects are less with valproic acid.

Author Affiliations
From the Department of Pediatrics, Children's Hospital, and the Division of Neurology, Ohio State University, Columbus.

Footnotes
Accepted for publication March 24, 1981.

Reprints not available.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Infantile Spasms and Lennox-Gastaut Syndrome
Trevathan
J Child Neurol 2002;17:2S9-2S22.
ABSTRACT  

Randomized trial of vigabatrin in patients with infantile spasms
Elterman et al.
Neurology 2001;57:1416-1421.
ABSTRACT | FULL TEXT  

Current Therapy for West Syndrome in Japan
Ito et al.
J Child Neurol 2000;15:424-428.
ABSTRACT  

Familial Idiopathic West Syndrome
Reiter et al.
J Child Neurol 2000;15:249-252.
ABSTRACT  

Topical Review: Vigabatrin in the Treatment of Infantile Spasms in Tuberous Sclerosis: Literature Review
Hancock and Osborne
J Child Neurol 1999;14:71-74.
ABSTRACT  

Medical Treatment of West Syndrome in Japan
Watanabe
J Child Neurol 1995;10:143-147.
ABSTRACT  

The Treatment of Infantile Spasms by Child Neurologists
Bobele and Bodensteiner
J Child Neurol 1994;9:432-435.
ABSTRACT  

Topical Review: Putative Neurotransmitter Abnormalities in Infantile Spasms: Cerebrospinal Fluid Neurochemistry and Drug Effects
Pranzatelli
J Child Neurol 1994;9:119-129.
ABSTRACT  

Unusual Variants of Infantile Spasms
Donat and Wright
J Child Neurol 1991;6:313-318.
ABSTRACT