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Stirling Carpenter, MD; Ramzy Yassa, MD; Rachel Ochs, MD

Arch Neurol. 1982;39(1):25-28.

Abstract
A patient with Kleine-Levin syndrome, typical except that onset was at 39 years of age, died during a symptomatic period. Autopsy disclosed recent and old lesions in the medial thalamus involving intralaminar, medial, and some dorsal nuclei as well as the pulvinar. Despite massive microglial infiltration, there was minimal neuronal loss. The hypothalamus was not involved. The findings suggest a viral cause for Kleine-Levin syndrome.

Author Affiliations
From the Department of Neurology-Neurosurgery, McGill University and Montreal Neurological Institute (Drs Carpenter and Ochs), and Douglas Hospital Centre (Dr Yassa), Montreal.

Footnotes
Accepted for publication April 1, 1981.

Reprint requests to Montreal Neurological Institute, 3801 University St, Montreal H3A 2B4, Quebec, Canada (Dr Carpenter).

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