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Myopathy Associated With Sclerodermal Facial Hemiatrophy
Robert Allen Schwartz, MD, MPH;
Andrew S. Tedesco, MD;
Lawrence Z. Stern, MD;
Anna M. Kaminska, MD, PhD;
John M. Haraldsen, MD;
David A. Grekin, MD
Arch Neurol. 1981;38(9):592-594.
Abstract
A patient who had linear scleroderma associated with ipsilateral hemiatrophy of the tongue and subsequent facial hemiatrophy was studied. Biopsy specimens of the plaque of scleroderma showed the skin changes of scleroderma as well as fascial and muscle changes. The fascia had an impressive plasma cell fasciitis with numerous plasma cells and scattered lymphohistiocytic cells. Histochemical study of the temporalis muscle underlying the plaque of circumscribed scleroderma disclosed severe localized atrophy of type 1 and type 2 fibers similar to the pathologic findings previously described in a patient with localized scleroderma.
Author Affiliations
From the Section of Dermatology (Drs Schwartz, Tedesco, and Haraldsen) and Department of Neurology (Drs Stern and Kaminska), University of Arizona College of Medicine, Tucson; Department of Neurology, Medical Academy of Warsaw (Dr Kaminska); and Department of Dermatology, University of California, San Francisco (Drs Schwartz and Grekin).
Footnotes
Accepted for publication March 15, 1981.
Reprint requests to Department of Neurology, University of Arizona Health Sciences Center, Tucson, AZ 85724 (Dr Stern).
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