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Effect of Levodopa on Thyroid Function and Prolactin ReleaseA Study in Patients With Parkinson's Disease
Patrick J. M. Lavin, MB BCh;
Marek J. Gawel, MA, MB, MRCP;
Prasanta K. Das, MB BS;
James Alaghband-Zadeh, MRCPath;
Frank Clifford Rose, MRCS, MB BS, FRCP(Lond)
Arch Neurol. 1981;38(12):759-760.
Abstract
Patients with Parkinson's disease who received a regimen of levodopa at levels that gave good clinical results did not have impaired thyroid function. The response of thyrotropin to intravenous administration of protirelin in these patients was not impaired by long-term levodopa therapy, but the prolactin response at 60 minutes was suppressed only in women. The response of prolactin to protirelin stimulation became similar to that found in both treated and untreated
Author Affiliations
From the Departments of Neurology (Drs Lavin, Gawel, Das, and Clifford Rose) and Chemical Pathology (Dr Alaghband-Zadeh), Charing Cross Hospital, London.
Footnotes
Accepted for publication Feb 26, 1981.
Reprint requests to Department of Neurology, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, England (Dr Clifford Rose).
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