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Clinical Significance

Daniel de la Paz, MD; Richard P. Brenner, MD

Arch Neurol. 1981;38(11):713-715.

Abstract
• Clinical data on 18 patients whose EEGs showed bilateral independent periodic lateralized epileptiform discharges (BIPLEDs) were reviewed and compared with those of 45 patients with periodic lateralized epileptiform discharges (PLEDs). A recent stroke was the most frequent cause of PLEDs (33%), while anoxic encephalopathy (28%) and CNS infection (28%) accounted for the majority of BIPLEDs. Focal neurologic deficits, focal seizures, and focal computed tomographic scan abnormalities were frequent in those with PLEDs, while coma predominated in the group with BIPLEDs (72% vs 24%). Mortality was also higher in patients with BIPLEDs—61% vs 29%.

Author Affiliations
From the Neurology Service, Veterans Administration Medical Center, and the Department of Neurology, University of New Mexico School of Medicine, Albuquerque.

Footnotes
Accepted for publication Jan 8, 1981.

Reprint requests to EEG Laboratory (127A), Veterans Administration Medical Center, 2100 Ridgecrest SE, Albuquerque, NM 87108 (Dr Brenner).

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