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  Vol. 38 No. 1, January 1981 TABLE OF CONTENTS
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Antifibrinolytic Therapy in Patients With Aneurysmal Subarachnoid Hemorrhage

A Report of the Cooperative Aneurysm Study

Harold P. Adams, Jr, MD; Donald W. Nibbelink, MD; James C. Torner, MS; A. L. Sahs, MD

Arch Neurol. 1981;38(1):25-29.


Abstract

• Antifibrinolytic therapy was used in 1,114 patients who had aneurysmal subarachnoid hemorrhage (SAH) and who were treated by the 13 institutions of the Cooperative Aneurysm Study. Patients were started on treatment within one week after SAH was diagnosed, and therapy was discontinued 14 days after the ictus. Rebleeding occurred in 10% of the treated patients. Overall mortality among the treated patients during the two weeks following hemorrhage was 10.7%. Though some minor and a few major side effects occurred, serious complications of therapy were infrequent.



Author Affiliations

From the Cooperative Aneurysm Study, Department of Neurology, University of Iowa, Iowa City. A list of additional participating investigators and their respective institutions follows in the "Acknowledgment" section.


Footnotes

Accepted for publication April 7, 1980.

Reprint requests to Cooperative Aneurysm Study, Department of Neurology, University of Iowa, Iowa City, IA 52242 (Dr Adams).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage: A Statement for Healthcare Professionals From a Special Writing Group of the Stroke Council, American Heart Association
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Current Strategies for the Management of Aneurysmal Subarachnoid Hemorrhage
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Arch Neurol 1987;44:769-774.
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Antifibrinolytics in Aneurysmal Subarachnoid Hemorrhage: Do They Have a Role? Maybe
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Arch Neurol 1987;44:114-115.
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Antifibrinolytics in Subarachnoid Hemorrhage: Do They Have a Role? No
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Arch Neurol 1987;44:116-118.
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